承担主要科研任务情况

（1）人参基于Ca2+介导的Drp1信号途径调控线粒体稳态作用机制研究，国家自然科学基金青年科学基金项目，24万元，2018-2020，1/9；

（2）基于线粒体稳态维系作用探讨人参“大补元气”生物学基础，财政部中央财政专项《名贵中药资源可持续利用能力建设项目》子课题，50万元，2019-2021，1/10；

（3）基于线粒体功能的人身核心功效物质基础与作用机制研究，国家自然科学基金，247万元，2020-2023，3/10；

（4）人参皂苷调控线粒体裂变分子机器维系自吞噬稳态延缓PD的共性机制研究，吉林省科技发展计划项目，20万元，2022-2024，1/7；

（5）靶向代谢重编程延缓干细胞衰老的人参单体成分筛选及靶点研究，吉林省人才开发专项，5万元，2022-2023，1/1；

（6）人参皂苷调控Drp1胞内转位阻滞线粒体动力学异常的分子机制研究，吉林省教育厅科学技术研究项目，2.5万元，2021-2022，1/5；

（7）复方归芎颗粒产品开发，横向课题，20万元，2022-2023，1/8；

（8）智能化药品生产设备研发-中药生产设备及生产线研发，吉林省科技发展计划项目，7万元，2021-2024，5/10；

（9）基于果蝇模式生物探讨人参皂苷调控线粒体分裂影响能量代谢的作用机制，长春中医药大学“杏林学者工程”青年科学家项目，4万元，2020-2021，主持

（1）吉林省科技进步二等奖：补益类中药传统功效科学诠释及健康产品开发，1/11，吉林省科学技术厅，2023

（2）吉林省科技进步二等奖：人参功效研究及健康产品开发与应用，5/13，吉林省科学技术厅，2020

（3）第五届全国大学生生命科学创新创业大赛优秀成果奖指导教师三等奖:基于指纹图谱和多指标定量测定的鹿茸饮片质量控制研究，1/1，全国大学生生命科学创新创业大赛组织委员会，2020

山药蛋白提取物在制备治疗勃起功能障碍的药物中的应用，已授权，ZL202010381144.1，2023，3/4

（1）Huanglianointment alleviates eczema by maintaining the balance of c-Jun and JunB andinhibiting AGE-RAGE-mediated pro-inflammation signaling pathway. Phytomedicine. 2022;105:154372.

（2）Ginsenoside Rg1 DelaysChronological Aging in a Yeast Model via CDC19- and SDH2-Mediated CellularMetabolism. Antioxidants (Basel). 2023;12(2):296.

（3）Herbal/Natural CompoundsResist Hallmarks of Brain Aging: From Molecular Mechanisms to TherapeuticStrategies. Antioxidants (Basel). 2023;12(4):920.

（4）Ginseng-derived nanoparticlesinduce skin cell proliferation and promote wound healing. J Ginseng Res. 2023; 47(1):133-143.

（5）Ginseng protein protects against mitochondrialdysfunction and neurodegeneration by inducing mitochondrial unfolded proteinresponse in Drosophila melanogaster PINK1 model of Parkinson's disease. J Ethnopharmacol. 2020;247:112213. 

（6） Ginsenosideson stem cells fate specification-a novel perspective. Front Cell Dev Biol. 2023;11:1190266. 

（7）Ginseng polysaccharideattenuates red blood cells oxidative stress injury by regulating red bloodcells glycolysis and liver gluconeogenesis. J Ethnopharmacol. 2023; 300:115716.

（8）The cold-soakingextract of Chinese yam (Dioscorea opposita Thunb.) protects against erectiledysfunction by ameliorating testicular function in hydrocortisone-inducedKDS-Yang rats and in oxidatively damaged TM3 cells. J Ethnopharmacol. 2020; 263:113223.

（9）GinsenosideRh2 inhibits HeLa cell energy metabolism and induces apoptosis by upregulatingvoltage‑dependent anion channel1.  Int J Mol Med. 2020; 46(5):1695-1706.

（10）GinsenosideRh2 represses autophagy to promote cervical cancer cell apoptosis duringstarvation. Chin Med. 2020; 15(1):118.

（11）Studies on the Regulation andMolecular Mechanism of Panax Ginseng Saponins on Senescence and RelatedBehaviors of Drosophila melanogaster. Front Aging Neurosci. 2022; 14:870326. 

（12）Ginsenoside Re InhibitsROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation ofNrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells. Molecules. 2019; 24(15):2687.

（13）GinsenosideRh2 Induces HeLa Apoptosis through Upregulating Endoplasmic ReticulumStress-Related and Downstream Apoptotic Gene Expression. Molecules. 2022; 27(22):7865. 

（14）Neuroprotectiveeffect of Ginsenoside Re against neurotoxin‑inducedParkinson's disease models via induction of Nrf2. Mol Med Rep. 2022; 25(6):215. 

（15）GinsenosideRh2 stimulates the production of mitochondrial reactive oxygen species andinduces apoptosis of cervical cancer cells by inhibiting mitochondrial electrontransfer chain complex. Mol Med Rep. 2021; 24(6):873.

（16）Puerariaprotein extract inhibits melanogenesis and promotes melanoma cell apoptosisthrough the regulation of MITF and mitochondrial‑relatedpathways. Mol Med Rep. 2023; 27(3):64. 

（17）UDPand NTF2 are the most consistently expressed genes in Panax ginseng roots atdifferent growth stages. Mol Med Rep. 2017; 15(6):4382-4390.

（18）Totalginsenosides induce autophagic cell death in cervical cancer cells accompaniedby downregulation of bone marrow stromal antigen-2. Exp Ther Med. 2021; 22(1):667. 

（19）Identification of novel reference genes using sika deer antlertranscriptome expression data and their validation for quantitative geneexpression analysis. Genes & Genomics. 2014, 36, 573–582.

（20）20(S)-GinsenosideRh2-induced apoptosis and protective autophagy in cervical cancer cells byinhibiting AMPK/mTOR pathway. Biosci Biotechnol Biochem. 2021; 86(1):92-103. 

（21）Hyperspectral imaging for in situ visual assessment of Industrial-Scale ginseng. Spectrochim Acta A Mol Biomol Spectrosc. 2024; 321:124700. 

（22）Total ginsenosides extend healthspan of aging Drosophila by suppressing imbalances in intestinal stem cells and microbiota. Phytomedicine. 2024; 129:155650.

（23）Ginseng total saponin improves red blood cell oxidative stress injury by regulating tyrosine phosphorylation and glycolysis in red blood cells. Phytomedicine. 2024;130:155785.