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吉林大学第一医院普通外科中心肝胆胰外二科副教授，博士研究生导师。世界内镜医师协会中国消化内镜分会常务委员，中国研究型医院胰腺学组青年委员，中华医学会消化内镜分会胰腺协作组青年委员，《中华消化外科杂志》菁英荟内镜外科学组委员。曾以访问学者身份赴德国波恩、美国纽约交流学习。擅长肝胆胰疾病的微创外科治疗，尤其是ERCP和超声内镜等内镜外科技术在胆胰疾病诊治中的应用，于国内率先开展Spyglass引导下的胆管癌精准射频消融术。以第一或通讯作者发表SCI论文20余篇，承担课题科研经费近150万元，拥有专利10余项，曾获吉林省科技进步二等奖及多项吉林大学医疗成果奖，培养博士及硕士研究生20人。
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支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg1. 《基于转录组测序的肝癌恶性进展与肿瘤免疫微环境的相关分子机制研究》 30万元 2023.11至2026.11 北京医学奖励基金会 负责人
2. 《齐墩果酸防治慢性肝损伤的产业化开发》 90万元 2019.01至2021.12 吉林省科技厅 负责人
3. 《miR-222–ADAM10–Notch3信号轴调控肝癌索拉非尼耐药的机制研究》 10万元 2020.01至2022.12 吉林省科技厅 负责人
4. 《miR-222–ADAM10调控肝癌进展的机制研究》 2.5万元 2020.01至2021.12 吉林省教育厅 负责人
5. 《金属支架联合射频消融治疗胆管恶性梗阻的临床疗效分析》 10万元 2019.01至2021.01 江苏恒瑞医药股份有限公司 负责人
6. 《miR-222调控ADAM10影响肝癌侵袭转移的机制研究》 15万元 2016.01至2018.12 吉林省科技厅 负责人
1. Chen J, Zhou H, Liu K. Normal weight and central obesity as predictors of increased all-cause mortality in metabolic dysfunction associated steatotic liver disease. J Hepatol. 2024;80:e143–5.
2. Fu C, Li X, Wang Y, Chen J, Yang Y, Liu K. Association between triglyceride glucose index-related indices with gallstone disease among US adults. Lipids Health Dis. 2024;23:203.
3. Wang Y, Liu K. Therapeutic potential of oleanolic acid in liver diseases. Naunyn Schmiedebergs Arch Pharmacol. 2024;397:4537–54.
4. Chen J, Zhou H, Liu K. A commentary on “The safety and efficacy between remimazolam and propofol in intravenous anaesthesia of endoscopy operation: a systematic review and meta-analysis.” Int J Surg. 2023;109:4371–2.
5. Fu C, Li X, Chen Y, Long X, Liu K. Lung cancer incidences after liver transplantation: A systematic review and meta-analysis. Cancer Med. 2023;12:16119–28.
6. Chen J, Zhou H, Jin H, Liu K. A nomogram for individually predicting the overall survival in colonic adenocarcinoma patients presenting with perineural invasion: a population study based on SEER database. Front Oncol. 2023;13:1152931.
7. Zhou H, Chen J, Jin H, Liu K. Genetic characteristics and clinical-specific survival prediction in elderly patients with gallbladder cancer: a genetic and population-based study. Front Endocrinol (Lausanne). 2023;14:1159235.
8. Chen J, Zhou H, Jin H, Liu K. The causal effects of thyroid function and lipids on cholelithiasis: A Mendelian randomization analysis. Front Endocrinol (Lausanne). 2023;14:1166740.
9. Chen J, Jin H, Zhou H, Hei X, Liu K. Research into the characteristic molecules significantly affecting liver cancer immunotherapy. Front Immunol. 2023;14:1029427.
10. Chen J, Jin H, Zhou H, Liu K. Effects of Metformin on Risk and Prognosis of Biliary Tract Cancer: A Systematic Review and Meta-Analysis. Medicina (Kaunas). 2023;59:298.
11. Chen J, Zhou H, Jin H, Liu K. Role of Inflammatory Factors in Mediating the Effect of Lipids on Nonalcoholic Fatty Liver Disease: A Two-Step, Multivariable Mendelian Randomization Study. Nutrients. 2022;14:4434.
12. Fa X, Song P, Fu Y, Deng Y, Liu K. Long non-coding RNA VPS9D1-AS1 facilitates cell proliferation, migration and stemness in hepatocellular carcinoma. Cancer Cell Int. 2021;21:131.
13. Zhou Q, Fu Y, Wen L, Deng Y, Chen J, Liu K. XPD Polymorphisms and Risk of Hepatocellular Carcinoma and Gastric Cancer: A Meta-Analysis. Technol Cancer Res Treat. 2021;20:1533033821990046.
14. Wen L-J, Chen J-H, Xu H-J, Yu Q, Liu K. Efficacy and Safety of Digital Single-Operator Cholangioscopy in the Diagnosis of Indeterminate Biliary Strictures by Targeted Biopsies: A Systematic Review and Meta-Analysis. Diagnostics (Basel). 2020;10:666.
15. Zhou Q, Chen J, Pan W, Chen Y, Wen L, Liu K. Incidence of kidney cancer after liver transplantation: a meta-analysis. Eur J Gastroenterol Hepatol. 2020;32:1273–8.
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